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Table 2 Integrated optical densities of the immunohistochemical staining for IL-1β and TNF-α

From: Preventive effects of the novel antimicrobial peptide Nal-P-113 in a rat Periodontitis model by limiting the growth of Porphyromonas gingivalis and modulating IL-1β and TNF-α production

 

Controls

P. gingivalis

Nal-P-113 (n = 12)

(n = 12)

(n = 12)

6.25 μg/mL

25 μg/mL

100 μg/mL

400 μg/mL

IL-1β

5.32 ± 0.93

54.26 ± 2.94

49.32 ± 9.81

40.50 ± 5.61

19.78 ± 3.40a

12.40 ± 2.51a

TNF-α

4.63 ± 0.57

27.11 ± 1.60

24.63 ± 5.17

20.94 ± 3.77

12.62 ± 2.67a

9.09 ± 2.07a

  1. a P < 0.05, compared with the P. gingivalis group