Centella asiatica modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)

Table 4 Modulation of caspase (−8, −9, −3/7) activities and ATP levels in 72 h C_LE treated PBMC’s

C_LE (mg/ml)	Caspase-8 (RLU × 10⁵)	Caspase-9 (RLU × 10⁵)	Caspase-3/7 (RLU × 10⁵)	ATP (RLU × 10⁵)
Control	30.688 ± 0.006	83.054 ± 0.009	132.624 ± 0.118	14.567 ± 0.184
0.05	21.726 ± 0.015^***	56.070 ± 0.003^***	128.471 ± 0.253^***	4.061 ± 0.014^***
0.2	10.436 ± 0.021^***	25.014 ± 0.007^***	57.946 ± 0.024^***	2.343 ± 0.029^***
0.4	42.625 ± 0.003^***	11.887 ± 0.005^***	35.842 ± 0.036^***	0.855 ± 0.002^***
0.8	14.157 ± 0.045^***	32.499 ± 0.288^***	43.376 ± 0.028^***	3.117 ± 0.007^***

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