Skip to main content

Advertisement

Table 2 Glucose and insulin concentrations obtained after the administration of an oral 3 g glucose load to diabetic rabbits (n = 6) treated with an intravenous metformin dose of 30 mg/kg

From: Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits

Time (min) Glucose (mg/dL) Insulin (mUI/L)
Standard chow (group 1) Supplemented chow (group 4) p values a Standard chow (group 1) Supplemented chow (group 4) p valuesa
0 399.9 ± 81.72 375.7 ± 152.0 0.737 0.616 ± 0.561 0.801 ± 0.464 0.547
30 461.6 ± 28.41 446.9 ± 154.2 0.824 0.990 ± 0.779 1.227 ± 0.814 0.617
60 496.4 ± 46.99 497.0 ± 122.1 0.991 1.297 ± 0.853 1.718 ± 1.202 0.500
120 552.3 ± 39.15 497.4 ± 102.5 0.248 1.000 ± 0.274 1.892 ± 1.186 0.103
180 471.7 ± 81.52 457.6 ± 117.4 0.814 0.573 ± 0.238 1.432 ± 0.940 0.055
  1. at Test