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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: What intrinsic factors influence responsiveness to acupuncture in pain?: a review of pre-clinical studies that used responder analysis

Fig. 2

A scheme of EA responsiveness-related factors and regions. The indicated specific regions, hypothalamus, PAG, pituitary gland and spinal cord, are well-known to be associated with pain regulation, and have been reconfirmed through researches on EA responsiveness. An asterisk implies intracerebroventricular injection. Responder-related factors and non-responder-related factors have been grouped in red and blue letters respectively. CCK AR, cholecystokinin A receptor; CCK BR, cholecystokinin B receptor; CCK-8, cholecystokinin octapeptide; Hypo, hypothalamus; PAG, periaqueductal grey; Pit. g., pituitary gland

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