Fig. 2From: What intrinsic factors influence responsiveness to acupuncture in pain?: a review of pre-clinical studies that used responder analysisA scheme of EA responsiveness-related factors and regions. The indicated specific regions, hypothalamus, PAG, pituitary gland and spinal cord, are well-known to be associated with pain regulation, and have been reconfirmed through researches on EA responsiveness. An asterisk implies intracerebroventricular injection. Responder-related factors and non-responder-related factors have been grouped in red and blue letters respectively. CCK AR, cholecystokinin A receptor; CCK BR, cholecystokinin B receptor; CCK-8, cholecystokinin octapeptide; Hypo, hypothalamus; PAG, periaqueductal grey; Pit. g., pituitary glandBack to article page