Skip to main content

Table 1 Effects of SS on expression of lipid metabolism related proteins

From: Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study

Protein name

protein ID

fold change

time(h)

protein description

Effect of SS on expression of Lipid transportation related proteins

Apoa4

P06728

3.28

8

Apolipoprotein A-IV

Apoa2

P09813

2.22

8

Apolipoprotein A-II

Apoa1

Q00623

1.47

4

Apolipoprotein A-I

Apoa5

Q8C7G5

1.06

2

Apolipoprotein A-V

Saa1

P05366

-1.85

24

Serum amyloid A-1 protein

Effect of SS on expression of Lipid metabolism related proteins

Lipa

Q9Z0M5

2.12

2

Lipase A

Fabp3

P11404

2.86

24

Fatty acid-binding protein

Scp2

P32020

1.33

24

Non-specific lipid-transfer protein

Fdx1

P46656

1.89

24

Adrenodoxin, mitochondrial

Acad11

Q80XL6

1.69

24

Acyl-CoA dehydrogenase family member 11

Acot2

Q9QYR9

1.20

48

Acyl-coenzyme A thioesterase 2, mitochondrial

Fdps

Q920E5

-1.55

24

Farnesyl pyrophosphate synthase

Sec14l2

Q99J08

-1.86

24

SEC14-like protein 2

Acsm1

Q91VA0

-1.69

8

Acyl-coenzyme A synthetase ACSM1

Dbi

P31786

-1.29

4

Acyl-CoA-binding protein

Acadl

P51174

-1.33

24

Long-chain specific acyl-CoA dehydrogenase

  1. Fold change: peak fold change of certain protein expression
  2. Time(h): time point after SS administration when reach peak fold change
  3. All fold changes are relative to Control group (time point 0 h)