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Table 5 Effect of test formulations on CFA induced rat paw edema

From: Effect of new polyherbal formulations DF1911, DF2112 and DF2813 on CFA induced inflammation in rat model

Groups

Paw edema (ml)

Day 7

Day 14

Day 21

Day 28

HC

0.06 ± 0.02***&&&$$$

0.05 ± 0.01***&&&$$$

0.03 ± 0.01***$$$

0.04 ± 0.02***$$$

NC

0.98 ± 0.1###

0.79 ± 0.07###

0.81 ± 0.07###&&

0.8 ± 0.06###&&

Diclo

0.88 ± 0.06###

0.66 ± 0.04###

0.32 ± 0.03**$$

0.35 ± 0.05**

Dasha

0.95 ± 0.08###

0.78 ± 0.12###

0.81 ± 0.06###&&

0.64 ± 0.03###

DF1911-LD

0.98 ± 0.05###

0.73 ± 0.04###

0.52 ± 0.06##

0.39 ± 0.06#**

DF1911-MD

0.88 ± 0.04###

0.74 ± 0.08###

0.51 ± 0.05##

0.43 ± 0.05#*

DF1911-HD

0.96 ± 0.06###

0.78 ± 0.05###

0.69 ± 0.08###&

0.54 ± 0.11###

DF2112-LD

0.86 ± 0.09###

0.86 ± 0.12###

0.53 ± 0.05##

0.41 ± 0.05#**

DF2112-MD

1 ± 0.09###

0.79 ± 0.06###

0.7 ± 0.11###

0.52 ± 0.11##

DF2112-HD

0.97 ± 0.13###

0.84 ± 0.13###

0.67 ± 0.15###

0.53 ± 0.07##

DF2813-LD

0.88 ± 0.07###

0.82 ± 0.1###

0.66 ± 0.13###

0.62 ± 0.13###

DF2813-MD

0.98 ± 0.1###

0.78 ± 0.04###

0.72 ± 0.09###&

0.7 ± 0.08###&

DF2813-HD

1.1 ± 0.08###

0.89 ± 0.09###

0.82 ± 0.15###&&

0.87 ± 0.12###&&&

  1. HC healthy control, NC negative control, Diclo diclofenac sodium, Dasha Dashamoola Kwatha, DF Dashamoola Formulation, LD lower dose, MD middle dose, HD higher dose. Values are expressed as Mean ± SEM (n = 6) using one way ANOVA followed by Dunnet’s multiple comparison test. # = p < 0.05, ## = p < 0.01, ###p < 0.001 when compared to HC; * = p < 0.05, ** = p < 0.01, *** = p < 0.001 when compared to NC; & = p < 0.05, && = p < 0.01, &&& = p < 0.001 when compared to Diclo; $$ = p < 0.01, $$$ = p < 0.001 when compared to Dasha