Fig. 4From: Anti-Hyperuricemic, Anti-Inflammatory and Analgesic Effects of Siegesbeckia orientalis L. Resulting from the Fraction with High Phenolic ContentCarrageenan was injected into the hind paw to produce thermal hyperalgesia in rats. The BuOH fraction (BuOH fr.) at the oral dose of 120 mg/kg significantly increased Δ withdrawal latency, inhibiting the inflammatory hyperalgesia response after 3 h of the treatment. Indomethacin (10 mg/kg) was used as a reference compound. Values are expressed in mean ± SEM from 8 animals per group. * p < 0.05, **p < 0.01 vs. hyperuricemic rats (control)Back to article page