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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Withania somnifera leaf alleviates cognitive dysfunction by enhancing hippocampal plasticity in high fat diet induced obesity model

Fig. 5

Schematic representation of the study. HFD regimen ameliorated key synaptic and cell survival pathways and ASH supplementation reduced stress levels and may have prevented memory and neuro-motor impairments caused due to HFD regimen. ASH exhibits a pleotropic neuroprotective phenomenon by targeting key pathways such as modulating BDNF mediated synaptic plasticity and cell survival in discrete brain regions, thereby promoting overall health and vitality

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