Table 2 Neuropeptides and CRP in healthy individuals
Reference | Participants | Study design | Interventions | Controls | Follow up | Outcomes | Findings |
|---|---|---|---|---|---|---|---|
Oken et al. (2010) [21] | 31 Dementia caregivers | RCT (pilot) | MM (N = 10) 6 weeks + common first-week session | Education (N = 11) 6 weeks + common first-week session Respite (N = 10) 7 weeks respite care | No | IL-6, TNF-α, HS-CRP, salivary cortisol | There were no pre- and post-intervention differences in the levels of HS-CRP between the different intervention conditions (p > 0.05). |
Creswell et al. (2012) [35] | 40 ≥ 55y | RCT (small) | MBSR (N = 20) 8 weeks | Wait-list Control (N = 20) | No | IL-6, CRP, pro-inflammatory gene expression | Compared to the control group, a decrease in log-transformed CRP between pre- and post-intervention (p = 0.08). |
Gallegos et al. (2013) [36] | 200 ≥ 65y | RCT | MBSR (N = 100) 8 weeks | Wait-list Control (N = 100) | 24 weeks | IL-6, IGF-1, IgM and IgG antibody response | There were positive effects of MBSR activities between IGF-1 levels and yoga, and sitting meditation (p < 0.01). |
Johnson et al. (2014) [22] | 281 Marine infantries | NRCT | MT (N = 147) 8 weeks | Usual training (N = 134) | No | plasma neuropeptide Y (NPY), norepinephrine | There were no significant pre- and post-intervention differences in plasma concentrations of NPY between MT intervention and the control group. The MT intervention group had lower plasma concentrations of NPY than the control group after the stressful training (p < 0.01). |