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Table 5 Effect of aqueous extract of C. occidentalis on blood lipid parameters

From: Hypolipidemic, antioxidant and anti-atherosclerogenic effect of aqueous extract leaves of Cassia. occidentalis Linn (Caesalpiniaceae) in diet-induced hypercholesterolemic rats

Experimental groups Lipid parameters (mg/dL)
TC TG VLDL-c HDL-c LDL-c LDL/HDL CT/HDL
HC rats + dH2O 156.09 ± 0.92 141.01 ± 0.63 28.21 ± 0.73 31.05 ± 0.48* 109.28 ± 0.49 5.87 ± 0.05 8.44 ± 0.82
HC +4 weeks treatment 240 mg/kg 135.51 ± 0.51* 101.62 ± 0.98* 20.33 ± 0.79* 26.73 ± 0.47 81.53 ± 0.5* 3.05 ± 0.07* 6.25 ± 0.34*
320 mg/kg 116.63 ± 0,54* 95.06 ± 0.57* 19.02 ± 0.66* 28.35 ± 0.58* 53.02 ± 0.83* 1.87 ± 0.06* 4.59 ± 0.16*
400 mg/kg 106.07 ± 0.69* 85.15 ± 0.64* 16.65 ± 0.38* 34.77 ± 0.6* 36.17 ± 0.34* 0.96 ± 0.04* 3.96 ± 0.15*
HC 4 weeks after treatment 240 mg/kg 130.12 ± 0.11* 98.13 ± 0.30* 18.30 ± 0.70* 27.12 ± 0.17 80.31 ± 0.15* 2.96 ± 0.02* 4.79 ± 0.13*
320 mg/kg 110.22 ± 0,34* 89.16 ± 0.33* 16.12 ± 0.25* 30.22 ± 0.32* 48.22 ± 0.23* 1.59 ± 0.03* 3.64 ± 0.11*
400 mg/kg 99.14 ± 0.44* 79.17 ± 0.24* 14.25 ± 0.31* 36.43 ± 0.21* 33.27 ± 0.14* 0.91 ± 0.02* 2.72 ± 0.12*
HC + Atorvastatin 1 mg/kg 95.23 ± 0.57* 86.84 ± 0.84* 17.27 ± 0.63* 31.05 ± 0.48* 39.06 ± 0.97* 1.26 ± 0.04* 3.29 ± 0.42*
NC rats 69.61 ± 0.92 69.46 ± 0.58 14.39 ± 0.57 30.83 ± 0.39 25.38 ± 0.66 0.83 ± 0.07 2.28 ± 0.07
  1. Data are represented as mean ± standard error of mean, n = 5. One-way ANOVA + LSD test against hypercholesterolemic (HC) rats: *P < 0.05. dH 2 O distilled water, HDL-c high density lipoprotein cholesterol, LDL-c low density lipoprotein cholesterol, NC normocholesterolemic, T treatment, TC total cholesterol, TG triglyceride, VLDL-c very low density lipoprotein cholesterol