Table 1 Comparative median effective concentration (EC50) values of the Buxus papillosa different parts extracts: leaves (BpL), stem (BpS) and roots (BpR) also leaves extract fractions: hexane (BpL-H) and aqueous (BpL-A) against various parameters in different isolated tissue preparations of rabbit and guinea-pig (atria)
From: Antispasmodic, bronchodilator, vasorelaxant and cardiosuppressant effects of Buxus papillosa
Sample | Jejunum | Trachea | Aorta | Atria | |||
|---|---|---|---|---|---|---|---|
Spontaneous | K+ (80 mM) | CCh (1 μM) | K+ (80 mM) | PE (1 μM) | K+ (80 mM) | Atrial force | |
BpL | 0.63 | 0.80 | 0.28 | 0.28 | 0.75 | 0.50 | 4.0 |
BpS | 1.02 | 1.20 | 0.26 | 0.85 | 0.98 | 1.3 | 1.80 |
BpR | 1.25 | 1.23 | 0.10 | 0.34 | 1.25 | 0.95 | 3.60 |
BpL-H | 0.55 | 0.73 | 0.25 | 0.31 | 0.98 | 1.1 | 1.50 |
BpL-A | 0.014 | 0.008 | 0.12 | 0.10 | 0.40 | 0.37 | 0.30 |