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Table 1 Effects of testosterone and, aqueous and methanolic extracts of F. asperifolia on body weight variation and relative organ weights of immature normal rats after four weeks of treatment

From: Androgenic effects of aqueous and methanolic extracts of Ficus asperifolia in male Wistar rats

Groups Body weight (g) Body weight variation (%) Relative organ weights (mg/100 g)
Initial Final Testes Epididymis Vas deferens Ventral prostate Seminal vesicles
Distilled water (10 ml/kg b.w.) 120.00 ± 6.4 173.40 ± 8.84 44.43 ± 1.94 1087.85 ± 20.38 232.78 ± 21.60 63.32 ± 5.05 41.37 ± 7.23 186.47 ± 30.51
5% Tween 80 (10 ml/kg b.w.) 118.80 ± 4.35 168.00 ± 6.77 41.51 ± 3.33 1099.65 ± 71.13 231.52 ± 27.78 57.65 ± 5.44 45.63 ± 7.42 145.48 ± 26.45
Testosterone (0.5 mg/kg b.w.) 120.40 ± 5.87 210.20 ± 12.3 74.41 ± 4.59** 416.25 ± 53.92*** 197.87 ± 7.31 66.32 ± 1.68 66.59 ± 11.06 484.98 ± 27.42***
F. asperifolia
 Aqueous extract
  100 mg/kg b.w. 121.20 ± 4.03 176.80 ± 7.11 45.81 ± 2.62≠≠ 1098.54 ± 77.69≠≠≠ 338.34 ± 29.42**≠≠≠ 81.64 ± 6.00* 76.72 ± 16.10* 273.40 ± 38.99*≠≠≠
  500 mg/kg b.w. 124.80 ± 7.08 187.80 ± 9.49 51.05 ± 4.91 1161.92 ± 75.33≠≠≠ 310.56 ± 23.81*≠≠ 64.34 ± 2.66 64.63 ± 5.09 243.13 ± 19.96≠≠≠
 Methanolic extract
  100 mg/kg b.w. 120.00 ± 6.38 190.60 ± 9.66 60.16 ± 10.40 1189.18 ± 53.47≠≠≠ 327.13 ± 24.35*≠≠ 70.77 ± 4.27 96.42 ± 11.72** 307.49 ± 28.97**≠≠≠
  500 mg/kg b.w. 123.40 ± 7.81 194.20 ± 6.45 59.95 ± 11.47 1279.15 ± 14.60*≠≠≠ 340.21 ± 32.27**≠≠≠ 72.76 ± 5.80 99.81 ± 13.00***≠α 308.94 ± 29.35**≠≠≠
  1. All values: Mean ± SEM; Number of rats per group = 5; *p < 0.05; ** p < 0.01; ***p < 0.001 compared to distilled water; p < 0.05; ≠≠ p < 0.01; ≠≠≠ p < 0.001 compared to testosterone; α p < 0.05 significantly different at equal dose of plant extracts