Skip to main content

Table 4 The effect of H. odorata extracts on intestinal transit in mice using charcoal meal as a marker

From: Antioxidant, antidiarrheal, hypoglycemic and thrombolytic activities of organic and aqueous extracts of Hopea odorata leaves and in silico PASS prediction of its isolated compounds

Treatment/Dose

% of intestine cross by marker

% of inhibition

Saline

84.85 ± 2.88

 

Loperamide

45.35 ± 1.72a

43.6 ± 2.14

MEHO200

59.89 ± 0.51b

25.63 ± 0.63

MEHO400

52.72 ± 1.11b

34.43 ± 1.38

EEHO200

57.15 ± 0.81b

28.1 ± 1.01

EEHO400

51.51 ± 0.97b

35.93 ± 1.21

AEHO200

62.05 ± 1.41b

22.82 ± 1.76

AEHO400

55.04 ± 1.54b

31.54 ± 1.91

  1. Values are presented as mean ± SEM for 5-6 rats. Data for % of intestine cross by H. odorata extracts, positive antidiarrheal control (Loperamide, 5 mg/kg p.o.) and normal control (saline) were processed by paired t-test analysis using Statistical package for social Science (SPSS for windows, version 21.0, IBM Corporation, New York, USA) followed by Dunnet test. a & b superscript letters are statistically significant to each other. Values with P < 0.05 are considered as statistically significant