Antioxidant, antidiarrheal, hypoglycemic and thrombolytic activities of organic and aqueous extracts of Hopea odorata leaves and in silico PASS prediction of its isolated compounds

Table 3 The effect of H. odorata extracts on castor oil induced enteropooling in mice

Treatment/Dose	Volume of intestinal content (ml)	Weight of intestinal content (g)	% Inhibition of intestinal content
Saline	0.24 ± 0.013	0.628 ± 0.033
Loperamide	0.13 ± 0.001	0.316 ± 0.002^a	48.2 ± 0.40
MEHO200	0.17 ± 0.007	0.396 ± 0.016^b	35.08 ± 2.67
MEHO400	0.14 ± 0.005	0.332 ± 0.010^a	45.57 ± 1.75
EEHO200	0.17 ± 0.004	0.388 ± 0.011^b	36.39 ± 1.83
EEHO400	0.14 ± 0.003	0.328 ± 0.006^a	46.23 ± 0.96
AEHO200	0.19 ± 0.004	0.428 ± 0.009^b	29.84 ± 1.41
AEHO400	0.16 ± 0.007	0.378 ± 0.017^a	38.03 ± 2.81

Values are presented as mean ± SEM for 5-6 rats. Data for the weight of intestinal content (g) by H. odorata extracts, positive antidiarrheal control (Loperamide, 5 mg/kg p.o.) and normal control (saline) were processed by paired t-test analysis using Statistical package for social Science (SPSS for windows, version 21.0, IBM Corporation, New York, USA) followed by Dunnet test. ^a & ^b superscript letters are statistically significant to each other. Values with P < 0.05 are considered as statistically significant

ISSN: 2662-7671