Fig. 1From: Dose-response effect of berberine on bile acid profile and gut microbiota in miceSchematic diagram of BAs EHC. This is the recirculation of BAs between the intestine and the liver. BAs are synthesized in the hepatocyte (from cholesterol) by Cyp7a1, 27a1, 7b1 and 8b1, released into bile, transformed by the gut microbiota, reabsorbed in the small intestine, and returned to the liver to be recycled. The major genes involved in the EHC are shownBack to article page