Antidiarrheal activity of 80 % methanol extract of the aerial part of Ajuga remota Benth (Lamiaceae) in mice

Table 1 Effect of the 80 % methanol extract of A. remota on castor oil induced diarrhea in mice

Group (mg/kg)	Onset of diarrhea (min)	Mean wt. of wet stools in 4 h (g)	Mean no. of wet stools in 4 h	Total no. of stools in 4 h	PI
Control	67.00 ± 2.51	0.69 ± .04	9.00 ± 1.09	11.00 ± 1.26
Loperamide5	174.33 ± 14.99^a***	0.22 ± .05^a***	3.00 ± .73 ^a***	4.00 ± .07 ^a***	66.7 %
MEAR 200	94.67 ± 1.64^bcd*	0.53 ± .02^b*cd*	6.83 ± .60^bcd*	10.00 ± .57^bcd*	12.9 %
MEAR 400	151.33 ± 1.42^a**f	0.35 ± .01^a***	4.17 ± .30^a**c	6.00 ± .73^af	53.7 %
MEAR 600	164.67 ± 15.14^a***	0.28 ± .05^a***	3.00 ± .63 ^a***	4.00 ± .85^a***	66.7 %
MEAR 800	190.00 ± 19.65 ^a***	0.15 ± .05^a**e	1.83 ± .60^a***	2.00 ± .94 ^a***	79.6 %

Values are expressed as Mean ± SEM.(n = 6 mice) ^aagainst control, ^bagainst standard, ^cagainst 800 MEAR, ^dagainst 600 MEAR, ^eagainst 400 MEAR, ^fagainst 200 MEAR ^* p < 0.05, ^** p < 0.01, ^*** p < 0.001., numbers refers to dose in mg/kg, PI refers to percent inhibition of defecation

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