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Table 2 Effects of acute intraperitoneal toxicity study after 24 h of administration of Bon-santé cleanser® in mice

From: Safety evaluation of Bon-santé cleanser® polyherbal in male Wistar rats

Treatments

D/TK

Sign of toxicity

Control (Distilled water, 0.1 ml i.p)

0/6

No toxic changes observed

BSC (200 mg/kg, i.p)

0/6

No toxic changes observed

BSC (400 mg/kg, i.p)

2/6

Slight weakness observed in at least 3 animals in first 2 h.

BSC (800 mg/kg, i.p)

6/6

Slight weakness observed in at least 3 animals in first 2 h.

BSC (1600 mg/kg, i.p)

6/6

Slight weakness observed in at least 3 animals in first 2 h.

  1. BSC Bon-santé cleanser®, K D/T Number of mice death/Total number of mice per group (n = 6). Acute Lethal Dose (LD50) = 600 mg/kg