Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: involvement of the antioxidant mechanisms

Table 9 Effect of PEBP, EABP and AQBP on total protein (TP; g/dL) and LDH (U/L) levels

Treatment	Dose (mg/kg)	TP (g/dL)	LDH (U/L)
Normal control	-	64.1 ± 3.8	408.2 ± 60.6
10 % DMSO + PCM		50.4 ± 1.4^a	1454.0 ± 255.0^a
Silymarin + PCM	200	69.1 ± 2.1^b	462.0 ± 59.8^b
PEBP + PCM	50	77.5 ± 3.5^b	1065.0 ± 127.3
	250	65.3 ± 1.4^b	371.0 ± 35.7^b
	500	76.5 ± 2.9^b	702.4 ± 90.7^b
EABP + PCM	50	88.1 ± 4.1^b	765.0 ± 199.9^b
	250	66.9 ± 0.9^b	415.0 ± 103.0^b
	500	83.9 ± 2.3^b	727.8 ± 130.8^b
AQBP + PCM	50	68.9 ± 3.8^b	689.2 ± 148.8^b
	250	70.4 ± 2.0^b	905.4 ± 65.2^b
	500	68.2 ± 1.9^b	525.2 ± 33.9^b

Values are expressed as means ± S.E.M. of six replicates
^aSignificant different (p < 0.05) when compared to the normal control group ((10 % DMSO + dH₂O)-treated) of the respective column
^bSignificant different (p < 0.05) when compared to the negative control group ((dH₂O + PCM)-treated) of the respective column

ISSN: 2662-7671