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Table 1 Effect of aqueous, methanol and chloroform crude extracts of leaves Ocimum lamiifolium on body weight and PCV of P. berghei infected mice

From: Antimalarial properties of crude extracts of seeds of Brucea antidysenterica and leaves of Ocimum lamiifolium

Extracts/treatments

Dose (mg/kg)

PCV

Body weight

D0

D-4

D0

D-4

NC

0

52.80 ± 0.48

40.58 ± 0.64b

27.90 ± 0.64

23.98 ± 1.46

dH2O

200

53.59 ± 2.88

44.75 ± 0. 96a

27.76 ± 0.20

26.88 ± 0.25a

 

400

55.09 ± 1.01

47.49 ± 2.22a

28.12 ± 0.13

29.56 ± 0.32a

 

600

51.98 ± 0.99

50.38 ± 0.52a

26.88 ± 0.15

27.20 ± 0.55a

CH3OH

200

54.66 ± 1.15

42.67 ± 0.67b

26.50 ± 1.41

26.29 ± 2.53a

 

400

51.69 ± 1.11

40.13 ± 1.84b

27.56 ± 1.41

26.22 ± 1.40a

 

600

53.98 ± 0.99

56.09 ± 0.44b

29.10 ± 2.58

30.09 ± 2.16a

CHCl3

200

56.94 ± 0.50

46.36 ± 0.6b

29.38 ± 2.39

24.36 ± 1.44b

 

400

54.14 ± 1.56

42.30 ± 0.87b

33.70 ± 8.76

28.23 ± 6.90b

 

600

51.68 ± 0.74

43.23 ± 0.66b

28.66 ± 2.55

25.00 ± 0.51b

CQ

25

54.73 ± 0.27

53.37 ± 0.21a

28.80 ± 0.23

30.97 ± 0.92b

  1. Key: Values are presented as mean ± SEM; n = 5; PCV packed cell volume, NC negative control (3 % tween 80), dH2O distilled water, CH 3 OH methanol, CHCl 3 chloroform, CQ chloroquine (positive control); a = the difference between day 0 and day 4 is not significant (P > 0.05); b = the difference between day 0 and day 4 is significant (P < 0.05)