Fig. 4
Representative photomicrographs of H&E staining on myocardial morphology (a) and interstitial fibrosis (b), with fibrotic tissue in blue and healthy cardiac tissue in pink and vascular fibrosis. Bar graph (c) showed a significant decrease in interstitial fibrosis (mm2) by SMY. Three rats in each group were analyzed in this experiment. (d) Effects of SMY on PICP, and PШNP (e) in rats with DOX-induced cardiomyopathy detected by ELISA. Six rats in each group were analyzed in ELISA assay and all data were represented as mean ± standard deviation. ** P < 0.01 versus the group control, *** P < 0.001 versus the group control; #P < 0.05 versus the group DOX, ###P < 0.001 versus the group DOX