Inhibitory effects of Cheongsangbangpoong-tang on both inflammatory acne lesions and facial heat in patients with acne vulgaris: A randomized controlled trial protocol

Table 2 Detailed study procedures

Items	Screening/run-in period	Visit 1 (baseline)	Visit 2	Visit 4 (endpoint)
Week of the trial	-1	0	4	8
Demographic information-taking	+
Informed consent form	+
General medical history-taking	+
Photographing the patient’s face Count of inflammatory/non-inflammatory lesions	+	+	+	+
Blood tests (AST, ALT, creatinine, serum cortisol, serum DHEA-S)	+			+
Urine pregnancy test	+		+	+
Digital infrared thermal imaging		+	+	+
Randomization & allocation	+
Distribution of treatment or placebo		+	+
Visual analogue scale		+	+	+
Investigator Global Assessments		+	+	+
Korean Acne Grading System		+	+	+
Pattern identification for acne	+
Monitoring adverse events			+	+
Compliance check			+	+
Blinding check				+

ISSN: 2662-7671