Fig. 6

Graph showing the concentrations of ciprofloxacin that accumulated in C. albicans in the presence of glucose only, DMSO, reserpine and compound B. Values are mean ± SD for N = 3 and *P < 0.05. Cells which were exposed to glucose had the least amount of the ciprofloxacin left in the cells, thus, indicating active efflux with glucose serving as a source of energy. Cells exposed to glucose and 5-hydroxy-7,4’-dimethoxyflavone had a higher amount of dye, thus, indicating the inhibition of the efflux of the ciprofloxacin from the cells. Reserpine, a standard inhibitor efflux inhibitor showed the inhibition of drug efflux and DMSO was the negative control and solvent used to dissolve the compound 5-hydroxy-7, 4’-dimethoxyflavone