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Table 1 Effect of IFA on the formation of non-fluorescent Nε-CML and carbonyl content in BSA incubated with MG at week 2

From: Isoferulic acid prevents methylglyoxal-induced protein glycation and DNA damage by free radical scavenging activity

Experiments Nε-CML Carbonyl content
  (ng/mL) (nmol/mg protain)
BSA 2.97 ± 0.21 0.14 ± 0.02
BSA / MG 5.75 ± 0.50a 1.89 ± 0.11a
BSA / MG / IFA (1.25 mM) 4.03 ± 0.44b 1.34 ± 0.40b
BSA / MG / IFA (2.5 mM) 3.93 ± 0.27b 0.97 ± 0.08b
BSA / MG / IFA (5 mM) 3.37 ± 0.44b 0.90 ± 0.11b
BSA / MG / AG (1.25 mM) 3.62 ± 0.40b 0.41 ± 0.08b
  1. The results are presented as mean ± SEM (n = 3). a p <0.05 when compared to BSA; b p <0.05 when compared to BSA/MG