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Table 5 Effect of AETS 100, 200 and 300 mg/kg in tail immersion test

From: Phytochemicals, antioxidant, antinociceptive and anti-inflammatory potential of the aqueous extract of Teucrium stocksianum bioss

Samples/standard Dose mg/kg Tail withdrawing time in sec
0 min 30 min 60 min 90 min 120 min
Normal saline 10 ml/kg 3.35 ± 0.11 3.48 ± 0.16 3.22 ± 0.032 3.39 ± 0.20 3.34 ± 0.19
AETS 100 mg/kg 3.35 ± 0.04n.s 3.61 ± 1.03 n.s 4.02 ± 1.03* 3.96 ± 0.4* 3.76 ± 1.04 *
200 mg/kg 3.36 ± 1.34 n.s 4.19 ± 1.07* 4.55 ± 0.07** 4.48 ± 0.1** 4.20 ± 2.10**
300 mg/kg 3.37 ± 0.4 n.s 4.80 ± 0.21* 5.36 ± 0.11** 5.30 ± 0.12** 5.03 ± 0.10**
TramadolR 30 mg/kg 3.5 ± 0.20 n.s 4.99 ± 1.33** 5.69 ± 0.02** 5.49 ± 0.06** 5.39 ± 0.05**
Antinociceptive effect of AETS and TramadolR antagonized by Naloxone
AETS 300 mg/kg 3.37 ± 1.05 n.s 4.10 ± 2.10 n.s 4.13 ± 1.07 n.s 4.20 ± 1.05 n.s 4.26 ± 1.70 n.s
TramadolR 30 mg/kg 3.38 ± 1.04 n.s 3.75 ± 2.41 n.s 3.72 ± 1.50 n.s 3.75 ± 1.02 n.s 3.70 ± 1.04 n.s
  1. Values expressed as mean ± SEM, The data was analyzed by ANOVA followed by Dunnett’s test, n.s shows statistically non significant values, **p <0.01 and *p <0.05 vs. control group (n = 6)