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Table 7 The antiviral activity of MBS extract on HSV-1 by the direct virucidal effect and the prophylactic effect on MRC-5 cell line

From: Novel antiviral activity of mung bean sprouts against respiratory syncytial virus and herpes simplex virus −1: an in vitro study on virally infected Vero and MRC-5 cell lines

Protocol Time aCC50 mg/ml b IC50 mg/ml cSI
dDVI 0 h 136.58 ± 55.08 24.17 ± 1.43 5.69 ± 0.35
  1 h 136.58 ± 55.08 13.8 ± 0.44 9.91 ± 0.31
  2 h 136.58 ± 55.08 7.62 ± 0.71 18.23 ± 1.69
Acyclovir 2 h 0.35 ± 0.005 0.014 ± 0.0005 22.56 ± 1.11
eIVR 30 min 136.58 ± 55.08 15.53 ± 0.74 8.83 ± 0.42
  1 h 136.58 ± 55.08 12.72 ± 1.12 10.9 ± 0.96
Acyclovir 1 h 0.37 ± 0.005 0.02 ± 0.003 15.04 ± 1.9
  1. Note: a cytotoxic concentration 50, b Inhibitory concentration 50, c selective index dDVI: the direct virus inactivation. eIVR: the inhibition in virus infection after specific cell treatment