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Table 7 The antiviral activity of MBS extract on HSV-1 by the direct virucidal effect and the prophylactic effect on MRC-5 cell line

From: Novel antiviral activity of mung bean sprouts against respiratory syncytial virus and herpes simplex virus −1: an in vitro study on virally infected Vero and MRC-5 cell lines

Protocol

Time

aCC50 mg/ml

b IC50 mg/ml

cSI

dDVI

0 h

136.58 ± 55.08

24.17 ± 1.43

5.69 ± 0.35

 

1 h

136.58 ± 55.08

13.8 ± 0.44

9.91 ± 0.31

 

2 h

136.58 ± 55.08

7.62 ± 0.71

18.23 ± 1.69

Acyclovir

2 h

0.35 ± 0.005

0.014 ± 0.0005

22.56 ± 1.11

eIVR

30 min

136.58 ± 55.08

15.53 ± 0.74

8.83 ± 0.42

 

1 h

136.58 ± 55.08

12.72 ± 1.12

10.9 ± 0.96

Acyclovir

1 h

0.37 ± 0.005

0.02 ± 0.003

15.04 ± 1.9

  1. Note: a cytotoxic concentration 50, b Inhibitory concentration 50, c selective index dDVI: the direct virus inactivation. eIVR: the inhibition in virus infection after specific cell treatment