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Table 2 Inhibitory effects of the TAFU on the tumor growth of S180 and LLC tumor models

From: Evaluation of antitumor property of extracts and steroidal alkaloids from the cultivated Bulbus Fritillariae ussuriensis and preliminary investigation of its mechanism of action

Groups Dose (mg/kg) No. of animals Weight of tumor (g) Inhibition (%)
S180 tumor model
Control - 10 1.20 ± 0.30 -
TAFU 20 10 1.22 ± 0.21 −1.46
  40 10 0.99 ± 0.10* 17.80
  80 10 0.62 ± 0.06** 48.56
CTX 20 10 0.53 ± 0.13*** 55.92
LLC tumor model
Control - 10 2.27 ± 0.16 -
TAFU 20 10 2.38 ± 0.17 −4.68
  40 10 2.11 ± 0.24 7.22
  80 10 1.36 ± 0.20** 39.96
CTX 20 10 0.94 ± 0.11*** 58.37
  1. The reported values are the means ± S.E.M. (n = 10). Significant differences compared to Control group are indicated by *P < 0.05, **P < 0.01 and ***P < 0.001.