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Table 3 Effect of CS on endogenous antioxidant and TBARS level in CMS rats

From: Evaluation of behavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress

  Groups
Parameters Control CMS CMS+DZM (2 mg/kg, p.o) CMS+CS
     125 mg/kg, p.o 250 mg/kg, p.o
SOD (U/mg protein)      
Brain 1.09 ± 0.03 0.21 ± 0.02** 0.98 ± 0.04†† 1.30 ± 0.07†† 1.54 ± 0.06††
Kidneys 0.75 ± 0.03 0.51 ± 0.05** 0.66 ± 0.05 0.71 ± 0.05†† 0.88 ± 0.01††
Adrenals 0.99 ± 0.10 0.56 ± 0.04** 0.85 ± 0.07 0.92 ± 0.09 0.83 ± 0.06
CAT (U/mg protein)      
Brain 1.77 ± 0.13 1.67 ± 0.28 1.50 ± 0.36 2.13 ± 0.41 2.63 ± 0.56
Kidneys 2.87 ± 0.35 1.43 ± 0.37* 1.83 ± 0.40 3.14 ± 0.24†† 3.93 ± 0.14††
Adrenals 1.27 ± 0.15 0.25 ± 0.02** 0.8 ± 0.06†† 0.41 ± 0.08 0.72 ± 0.09††
Ascorbic acid (μg/mg protein)      
Brain 13.75 ± 3.50 14.25 ± 3.50 12.50 ± 3.13 10.38 ± 2.63 12.25 ± 3.13
Kidneys 17.83 ± 2.00 23.33 ± 1.67* 18.33 ± 1.50 20.50 ± 1.17 18.33 ± 0.67
Adrenals 43.33 ± 4.7 90.00 ± 11.33** 49.67 ± 6.53†† 58.67 ± 9.13 68.67 ± 6.67
TBARS (nmol of MDA/mg tissue)      
Brain 0.15 ± 0.02 0.89 ± 0.12** 0.42 ± 0.10†† 0.48 ± 0.07†† 0.38 ± 0.09††
Kidneys 0.19 ± 0.02 0.84 ± 0.07** 0.53 ± 0.05 0.58 ± 0.04 0.38 ± 0.19††
Adrenals 0.28 ± 0.24 1.23 ± 0.13** 1.04 ± 0.21 1.32 ± 0.28 1.09 ± 0.33
  1. Data are expressed as mean ± SEM. * and indicates statistical significance in comparison to control and stress groups respectively and denotes *, † p < 0.05 and **, † † p < 0.01