Skip to main content

Advertisement

Table 2 Dosage effect of MAK-4 and MAK-5 on H-ras-induced cell transformation in Rat 6 cells

From: MAK-4 and -5 supplemented diet inhibits liver carcinogenesis in mice

Treatment Exogenous H-ras gene Cytotoxicity (% survival) Relative number of foci
Mock control - 100 0
None + 100 1.0
MAK-4:    
200 μg/ml + 132 1.75
500 μg/ml + 98 1.29
1000 μg/ml + 92 1.35
MAK-5:    
200 μg/ml + 135 0.69
500 μg/ml + 64 0.28
1000 μg/ml + 48 0.26
  1. Data were obtained from two individual experiments by focus formation assay. Triplicate plates were used for each experiment. Experimental procedures were the same as indicated in Table 1.