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Figure 4 | BMC Complementary and Alternative Medicine

Figure 4

From: The chalcone butein from Rhus verniciflua Stokes inhibits clonogenic growth of human breast cancer cells co-cultured with fibroblasts

Figure 4

Co-culture of breast cancer cells with fibroblasts pre-treated with butein. Pre-treatment of the fibroblasts with butein at concentrations greater than or equal to 2.5 μg/mL completely eliminated or substantially reduced clonogenic growth of co-cultured breast cancer cells, suggesting an indirect mechanism of action that interferes with the interaction between fibroblasts and breast cancer cells.

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