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Table 5 Mean changes of VAS that assessed pain and stiffness, Lequesne's functional index and time for climbing up 10 steps in intent-to-treat patients (n = 100/group).

From: Chinese herbal recipe versus diclofenac in symptomatic treatment of osteoarthritis of the knee: a randomized controlled trial [ISRCTN70292892]

Variable Treatment Group Week 0–1 Week 0–2 Week 0–3 Week 0–4
VAS that assessed pain (mm)
   Walking pain DJW -16.96 (1.68) -26.82 (1.97) -36.54 (2.31) -46.48 (2.41)
  Diclofenac -20.70 (1.60) -29.80 (1.95) -40.58 (2.26) -50.47 (2.38)
   Standing pain DJW -12.61 (1.80) -20.81 (2.23) -28.13 (2.28) -35.53 (2.34)
  Diclofenac -15.93 (1.33) -25.33 (1.83) -32.41 (2.04) -40.66 (2.25)
   Pain during climbing up and down stairs DJW -16.78 (1.95) -26.68 (2.30) -34.93 (2.26) -44.67 (2.22)
  Diclofenac -18.79 (1.40) -30.08 (1.91) -38.11 (2.04) -46.86 (2.35)
   Night pain DJW -16.71 (2.32) -26.60 (2.25) -34.47 (2.42) -40.88 (2.59)
  Diclofenac -19.52 (1.98) -27.58 (2.30) -33.43 (2.51) -39.80 (2.81)
   Resting pain DJW -11.23 (1.24) -18.52 (1.46) -25.84 (1.86) -31.06 (2.02)
  Diclofenac -14.28 (1.34) -20.86 (1.91) -25.82 (2.07) -30.54 (2.38)
   Total paina DJW -74.27 (6.53) -119.42 (7.42) -159.90 (7.85) -198.61 (8.51)
  Diclofenac -89.21 (5.25) -133.64 (7.02) -170.34 (7.65) -208.33 (9.03)
   Pain during the most painful knee movement DJW -18.94 (2.11) -32.48 (2.63) -44.56 (2.77) -55.44 (2.67)
  Diclofenac -24.38 (2.10) -37.53 (2.51) -48.07 (2.57) -58.33 (2.59)
VAS that assessed stiffness (mm)
   Morning stiffness DJW -16.93 (1.98) -25.50 (2.24) -33.87 (2.46) -41.19 (2.58)
  Diclofenac -19.59 (1.69) -29.80 (2.10) -38.13 (2.47) -45.42 (2.63)
   Stiffness after rest DJW -16.83 (1.97) -29.12 (2.41) -39.48 (2.50) -48.91 (2.54)
  Diclofenac -20.74 (1.72) -30.91 (2.07) -42.22 (2.29) -51.55 (2.40)
   Total stiffnessb DJW -33.76 (3.48) -54.62 (4.02) -73.35 (4.21) -90.10 (4.27)
  Diclofenac -40.33 (3.05) -60.71 (3.72) -80.35 (4.21) -96.97 (4.47)
Lequesne's functional index (score) DJW -2.60 (0.34) -3.15 (0.32) -4.28 (0.37) -5.29 (0.38)
  Diclofenac -3.92 (0.31) -4.16 (0.32) -5.22 (0.36) -6.16 (0.40)
Time for climbing up 10 steps (s) DJW -1.79 (0.33) -2.02 (0.31) -2.50 (0.32) -2.94 (0.32)
  Diclofenac -2.05 (0.31) -2.18 (0.34) -2.71 (0.34) -3.13 (0.33)
  1. Data represent mean (SD). aSummation of VAS that assessed walking pain, standing pain, pain during climbing up and down stairs, night pain and resting pain. bSummation of VAS that assessed morning stiffness and stiffness after rest. p < 0.05 versus the DJW group at the same duration of treatment.