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Table 5 Effect of the chloroform fraction of Croton macrostachys on on rectal temperature of Plasmodium berghei infected mice in the Rane’s test

From: In vivo antimalarial activity of the crude leaf extract and solvent fractions of Croton macrostachyus Hocsht. (Euphorbiaceae) against Plasmodium berghei in mice

Group

Day 0

Day 3

Day 4

Day 5

Day 6

Day 7

Control

37.25±0.21

34.05±0.15

34.08±0.19

33.48±0.26

33.53±0.21

32.75±0.16

CM200

37.48±0.3

33.38±0.21

34.48±0.33

34.76±0.27

35.62±0.26

36.43±0.24a3,b1

CM400

37.48±0.22

33.38±0.38

34.53±0.37

34.15±0.23

36.05±0.25

36.62±0.21a3

CM600

37.50± 0.21

33.64±0.32

33.91±0.26

35.74±0.14

36.50±0.28

36.91±0.13a3

CQ25

37.32±0.23

33.92±0.32

34.67±0.24

35.65±0.29

37.13±0.19

37.40±0.19a3

  1. Data are expressed as mean ± SEM for six mice per group; a = compared to controls, b = to chloroquine 25 mg/kg; 1 = p<0.05; 3=p<0.001, CQ = chloroquine.