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Table 3 Protective effect of curcumin on paracetamol induced changes in hepatic antioxidant activity in Wistar rats

From: Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats

 

Control

Curcumin

Paracetamol

Curcumin + Paracetamol

MDA (nmol/g tissue)

9.78 ± 1.9

10.7 ± 1.0

18.2 ± 0.5*

12.6 ± 0.4#

Catalase (U/g tissue)

33 ± 6.1

37 ± 1.1*

21 ± 0.4*

33.9 ± 2.6#

  1. Values are means ± standard error (SEM) 3 independent experiments per each treatment. Values are statistically significant at *p < 0.05 Vs. control and #p < 0.05 Vs. paracetamol group.