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Table 1 Histological score of articular cartilage

From: Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies

Femoral condyle

Vehicle

Biochanin A (5μM )

Biochanin A (50μM)

Structural changes

3.23 ± 0.31

2.76 ± 0.15

1.8 ± 0.1*

Cellular changes

2.67 ± 0.15

2.27 ± 0.25

1.87 ± 0.15*

Safranin staining

2.9 ± 0.1

2.53 ± 0.21

1.94 ± 0.15*

Total score

8.8 ± 0.53

7.57 ± 0.40*

5.6 ± 0.26*

  1. Values are the mean ± SD. *p < 0.05 compared with vehicle group.