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Table 2 Cytotoxicity results of A.carnosus extracts by SRB assay

From: Cytotoxic potential of Anisochilus carnosus (L.f.) wall and estimation of luteolin content by HPLC

Concentration (μg/ml) % Viability
Aqueous extract Ethanolic extract Pet. ether extract Paclitaxel
0 100 ± 6.198 100 ± 6.198 100 ± 6.198 100 ± 2.44
6.25 - - - 86.25 ± 0.441**
12.5 - - - 45.36 ± 0.582**
25 89.50 ± 0.883 80.57 ± 1.972* 46.68 ± 5.838** 29.51 ± 1.54**
50 71.01 ± 2.141** 59.04 ± 3.507** 36.89 ± 3.525** 16.46 ± 2.313**
100 61.44 ± 1.129** 36.38 ± 1.396** 18.73 ± 2.505** -
200 52.43 ± 0.745** 11.85 ± 2.371** 10.84 ± 2.741** -
IC 50 value 211.26 87.24 22.5a 13.91a
  1. Results were expressed as Mean ± SEM (n = 3) and analysed using one-way ANOVA followed by Tukey’s post hoc test of significance [where different alphabets a, b denote significant difference (p <0.05)]. Statistical comparison between the mean % viability of each extract and its negative control was performed using one-way ANOVA followed by Dunnett’s post hoc test of significance wherein *p <0.05 and **p <0.01 were considered to be statistically significant and very statistically significant compared to negative control. A.carnosus extracts were not tested at concentrations of 200, 100, 50, 25 μg/ml (they were not tested at concentrations of 6.25 and 12.5 μg/ml). Paclitaxel was tested at concentrations of 6.25, 12.5, 25 and 50 μg/ml.