Skip to main content

Advertisement

Table 1 Effect of ETAS on pentobarbitone-induced sleeping time in mice

From: Central-stimulating and analgesic activity of the ethanolic extract of Alternanthera sessilis in mice

Treatment (n=6) Dose (mg/kg) Onset of sleep (min) % Increase of onset of sleep Duration of sleep (min) % Decrease of duration of sleep
Control - 11.24 ± 1.80 - 101.57 ± 2.67 -
Caffeine 20 58.63 ± 1.84* 421.62 62.56 ± 2.23* 38.41
A. sessilis 250 32.45 ± 2.89*,# 188.70 88.67 ± 2.90# 12.70
500 53.67 ± 2.60* 377.49 78.13 ± 2.31*,# 23.08
  1. Values are mean ± SEM. *p < 0.001 vs. control, #p < 0.01 vs. caffeine, the data was analyzed by one way ANOVA followed by Bonferroni’s test.