Effects of clary sage on SBP and HR in chronic immobilization stress induced rats. Rats were exposed to immobilization stress (2 h/day) for 14 days, with administration of almond oil, clary sage (5%, 10%, or 20%) or nifedipine (10 mg/kg) once daily. (A) SBP and (B) HR were measured using a tail cuff and pulse transducer. Data represent mean values ± SEM (n = 7-9 per group). *P <0.05, **P <0.01, ***P <0.001 compared to the stress vehicle group.