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Table 6 Skin whitening activity (%) of CPE, AA and PBE using mushroom tyrosinase against kojic acid (KA)

From: Phenolic composition, antioxidant, anti-wrinkles and tyrosinase inhibitory activities of cocoa pod extract

Sample Concentration, μg/ml IC 50     
  7.8      15.6      31.3      62.5      125      250      500      1000       
KA 18.07 ± 0.25 22.44 ± 0.04 11.17 ± 1.71 11.71 ± 1.27 24.12 ± 4.89 52.22 ± 7.46 47.78 ± 4.07 68.80 ± 2.89 572.28
AA 8.29 ± 0.81 7.25 ± 0.08 14.15 ± 2.88bγδε 13.51 ± 1.40c δ 11.84 ± 0.47 25.26 ± 0.89d 18.61 ± 2.71 29.62 ± 1.51d€ 670.82
PBE 42.57 ± 1.98aβγ 41.22 ± 2.21 43.14 ± 2.78aβγ 44.16 ± 0.79 48.31 ± 2.71 36.67 ± 0.40c α 49.10 ± 2.97 77.65 ± 4.51 315.16
CPE 16.17 ± 2.67 21.52 ± 2.29 16.97 ± 3.48bαβ 27.78 ± 3.19 41.99 ± 6.93 62.23 ± 0.47 65.87 ± 4.20 86.51 ± 2.12a € 357.95
  1. a b c dDifferent alphabet in column means significantly different within concentration.
  2. α β γ δ ε € £different symbol means significantly different within concentration for each sample in row.