Proteome profiling of lipopolysaccharide induced L6 rat skeletal muscle cells response to flavonoids from Scutellaria baicalensis Georgi

Table 1 Spectral data of the 16 flavonoids identified from Korean S. baicalensis G. using HPLC-MS/MS

No	Compound	Rt (min)	[M-H]^-/[M + H]⁺	MS/MS	^aQuantity (mg/kg)
1	Pentahydroxyflavanone derivative	20.64	629	303 285 275 217 201 177 149 125	212.543 ± 1.074
2	Pentahydroxyflavanone	23.49	303	303 285 275 259 217 193 177 149 125 109	16.670 ± 0.188
3	Viscidulin I –O– diglucoside	25.98	625	301 283 273 258 229 185 151 125	21.220 ± 0.440
4.	Pentahydroxyflavone	29.31	301	301 283 269 259 240 191 179 161 139 124 121 109	17.657 ± 0.204
5	N.I	34.65	647(+)	647 501 467 347 321 303 285	-
6	Viscidulin III –O– glucoside	35.22	507	345 330 315	-
7	Tetrahydroxyflavone	37.69	285	285 268 241 217 199 177 151 133 107	43.056 ± 0.112
8	Iridin	40.20	521	383 359 344 329 313 300 285 212	21.472 ± 0.415
9	Eriodictyol (4′-hydroxynaringenin)	42.25	289(+)	289 271 247 179 163 153 147	45.679 ± 0.782
10	Puerarin	43.24	415	415 295 267 253 223	7.003 ± 0.022
11	Viscidulin III	43.88	347(+)	347 332 317 314 289 286 183 169 150 142	-
12	Pentahydroxyflavone	45.11	301	301 283 269 241 225 197 179 165 161 139 133 124 107	20.622 ± 0.036
13	N.I	52.55	675	675 529 481 361 335 317 285	-
14	Baicalin	53.67	447(+)	447 343 271 253 225 169 149 123105	3.035 ± 0.013
15	Scutellarein	56.25	285	285 267 257 239 213 195 185 167 165 137 119 117	21.017 ± 0.133
16	Isoscutellarein	57.35	285	285 267 257 241 239 229 213 185 167 165 137 119 117	7.882 ± 0.009

^aQuantity data are the mean ± SD of three replicates determinations by HPLC-UV method.
N.I: Not Identified.

ISSN: 2662-7671