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Table 2 Effect of Polygonum minus extract on paw volume and percentage inhibition in carrageenan induced paw edema

From: Anti-inflammatory effects of Polygonum minus (Huds) extract (Lineminus™) in in-vitro enzyme assays and carrageenan induced paw edema

Groups & Dose

Mean paw volume ± SEM (mL) (% Inhibition a )

0 hr

2 hr

4 hr

6 hr

Vehicle control (0.5% CMC) 0 mg/kg b.w.

1.35 ± 0.03

1.46 ± 0.03

1.50 ± 0.03

1.42 ± 0.04

Standard (diclofenac)

1.38 ± 0.04

1.50 ± 0.02

1.37 ± 0.03*

1.41 ± 0.04

10 mg/kg b.w.

(-2.22%)

(-2.74%)

(8.66%)

(0.70%)

Polygonum minus aqueous extract

1.33 ± 0.02

1.47 ± 0.04

1.32 ± 0.03**

1.40 ± 0.05

100 mg/kg b.w.

(1.48%)

(-0.68%)

(12.00%)

(1.41%)

Polygonum minus aqueous extract

1.38 ± 0.03

1.42 ± 0.02

1.34 ± 0.02**

1.35 ± 0.04

300 mg/kg b.w.

(-2.22%)

(2.74%)

(10.67%)

(4.93%)

  1. Values are expressed as mean ± SEM, n = 8 (4Male + 4Female); (-) = No inhibition.
  2. aInhibition is reported as a percentage compared to control.
  3. *Vehicle control vs standard (p < 0.05).
  4. **Vehicle control vs Polygonum minus (100 mg/kg) / Polygonum minus (300 mg/kg) (p < 0.01).
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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