Figure 1

Evaluating the antipruritic effect of different thermal stimulations over Quchi (LI11) acupoint on compound 48/80-induced scratching behavior. (A) Flow chart depicting steps involved in the study. (B) The probes (arrows) of constant temperature tissue cooling apparatus. (C) Localization and (D) operation of LI11 acupoint stimulated in the mice. It is located at the depression medial to the extensor carpi radialis, at the lateral end of the cubital crease. The sham point was located at the midpoint of the acromial part of the deltoid muscle, which is distant from classical acupoints.