Figure 1From: Astragalosides from Radix Astragali benefits experimental autoimmune encephalomyelitis in C57BL /6 mice at multiple levels Effects of AST on EAE progression and body weight in mice. A) Comparison of mean clinical scores after EAE induction. AST was administered at three different dosages (H: 50 mg/kg/day, M: 25 mg/kg/day, L: 10 mg/kg/day) i.p. from the day before MOG35–55 immunization and lasted for 14 days as well as ASI (10 mg/kg/day). Methylprednisolone (MPD) served as positive control drug was given at 50 mg/kg/day i.p. from the day 8 to day 10 post-immunization. B) Change of body weight among different group mice. All data are presented as mean±standard error of mean (n = 14). **p < 0.01; ***p < 0.001 vs EAE group.Back to article page