Table 3 Plasma metabolites detected in the sham-operated and model animals 21 days after the operation

TAC

19.60

Citric acid

1.92 ± 1.909

4.33 ± 1.240^▲

0.026

24.18

cAMP

0.27 ± 0.092

0.10 ± 0.052^▽

0.006

Amino acid metabolism

8.01

Ethylbis(trimethylsilyl)amine

0.79 ± 0.143

1.29 ± 0.437^▲

0.048

9.60

Alanine

0.64 ± 0.037

1.08 ± 0.311^▲

0.036

10.94

L-Norvaline

1.26 ± 0.616

2.28 ± 0.687^▲

0.029

11.67

L-Valine

0.12 ± 0.032

0.29 ± 0.117^▲

0.014

12.00

Urea

8.05 ± 1.569

13.41 ± 2.833^▲▲

0.008

13.17

Glycine

0.57 ± 0.247

0.27 ± 0.057^▽

0.028

14.11

L-Serine

1.36 ± 0.301

1.76 ± 0.476^▲▲

0.001

16.94

L-Proline

0.57 ± 0.232

0.11 ± 0.027^▽▽

0.005

Glucose metabolism

21.31

Glucopyranose

0.22 ± 0.050

20.64 ± 1.144^▲▲

0.000

22.52

Glucopyranoside

0.07 ± 0.017

0.16 ± 0.046^▲

0.023

Fatty acid metabolism

8.77

Lactic acid

1.48 ± 0.036

2.62 ± 0.345^▲▲

0.000

9.25

Acetic acid

0.29 ± 0.073

0.47 ± 0.075^▲▲

0.004

14.80

Butanoic acid

0.39 ± 0.065

0.80 ± 0.212^▲▲

0.009

17.48

Dodecanoic acid

0.40 ± 0.050

1.02 ± 0.465^▲

0.021

21.73

Hexadecanoic acid

1.87 ± 0.320

2.67 ± 0.398^▲▲

0.006

23.54

Octadecanoic acid

3.58 ± 0.965

5.49 ± 0.670^▲▲

0.004

25.99

Octadecatrienoic acid

0.07 ± 0.036

0.02 ± 0.117^▽

0.022

29.84

Monolinoleoylglycerol

1.13 ± 0.562

0.38 ± 0.201^▽

0.040