Figure 1From: Inhibition of hematopoietic prostaglandin D2 Synthase (H-PGDS) by an alkaloid extract from Combretum molle The inhibitory effect of C. molle on GST Sigma with increasing concentration of plant extract. The concentration of natural product required to bring about 50% inhibition of GST activity, the IC50 value, was determined by plotting sigmoidal dose response curves of percent enzyme activity vs. log natural product concentration using GraphPad Prism version 5.00 (GraphPad™ Software Inc., San Diego, California, USA). The IC50 value determined from the graph was 13.7 μg/ml.Back to article page