Type of cell line | GTT:HC | IC50a[μg/ml] | GTTb[μg/ml] | HCb[μg/ml] | Combination Indexc(CI) |
---|
1321N1 | 10 : 3 | 12 | 100 | 75 | 0.55 ± 0.07 |
SW1783 | 20 : 1 | 2 | 79 | 95 | 0.54 ± 0.03 |
LN18 | 2 : 3 | 29 | 42 | 119 | 0.73 ± 0.03 |
-
aIC50 of combined compounds.
-
bIC50 of individual compound.
-
cCI < 1.0 indicates synergism; 0.9 < CI < 1.10, near additive; CI > 1.10 indicates antagonism.
- The data are the average of three independent experiments.