From: Mutagenicity and antimutagenicity of six Brazilian Byrsonima species assessed by the Ames test
Mutagens (M) | NPDb | MMCc | AFB1 d | B[a]Pe | ||||
---|---|---|---|---|---|---|---|---|
Strains | TA 98 (-S9) | TA 102 (-S9) | TA 100 (+S9) | TA 98 (+S9) | ||||
Treatment (mg/plate) | M ± SD and (%I) | Treatment (mg/plate) | M ± SD and (%I) | Treatment (mg/plate) | M ± SD and (%I) | Treatment (mg/plate) | M ± SD and (%I) | |
B. verbascifolia | ||||||||
0 a | 18 ± 4 | 0 a | 487 ± 81 | 0 a | 114 ± 6 | 0 a | 36 ± 5 | |
0.013 + M b | 483 ± 40** (45) | 0.094 + M c | 1502 ± 138 (6) | 0.125 + M d | 213 ± 7*** (85) | 0.049 + M e | 102 ± 24*** (44) | |
0.025 + M b | 454 ± 60*** (48) | 0.188 + M c | 1296 ± 24 (19) | 0.250 + M d | 131 ± 27*** (91) | 0.098 + M e | 78 ± 6*** (57) | |
0.050 + M b | 550 ± 41** (37) | 0.375 + M c | 1366 ± 21 (15) | 0.500 + M d | 125 ± 16*** (91) | 0.195 + M e | 85 ± 9*** (54) | |
0.100 + M b | 628 ± 138* (28) | 0.750 + M c | 1380 ± 4 (14) | 1.000 + M d | 132 ± 13*** (91) | 0.390 + M e | 41 ± 5*** (78) | |
0.200 + M b | 1001 ± 137 | 1.500 + M c | 1381 ± 58 (14) | 2.000 + M d | 132 ± 24*** (91) | 0.780 + M e | 34 ± 7*** (82) | |
M b | 876 ± 30 | M c | 1601 ± 226 | M d | 1399 ± 34 | M e | 184 ± 8 | |
B. correifolia | ||||||||
0 a | 18 ± 4 | 0 a | 464 ± 48 | 0 a | 104 ± 15 | 0 a | 36 ± 5 | |
0.013 + M b | 440 ± 57*** (50) | 0.031 + M c | 1208 ± 15 (15) | 0.008 + M d | 353 ± 59*** (60) | 0.250 + M e | 34 ± 6*** (82) | |
0.025 + M b | 426 ± 2*** (51) | 0.063 + M c | 1126 ± 66* (20) | 0.016 + M d | 248 ± 38*** (72) | 0.500 + M e | 31 ± 6*** (83) | |
0.050+ M b | 497 ± 39*** (43) | 0.125 + M c | 1152 ± 74* (19) | 0.031 + M d | 370 ± 49*** (58) | 1.000 + M e | 32 ± 6*** (82) | |
0.100+ M b | 593 ± 20*** (32) | 0.250 + M c | 1205 ± 52 (15) | 0.063 + M d | 180 ± 57*** (80) | 2.000 + M e | 31 ± 5*** (83) | |
0.200+ M b | 521 ± 61*** (41) | 0.500 + M c | 1129 ± 146*(20) | 0.125 + M d | 206 ± 46*** (77) | 4.000 + M e | 39 ± 3*** (79) | |
M b | 876 ± 30 | M c | 1414 ± 61 | M d | 883 ± 80 | M e | 184 ± 8 | |
B. fagifolia | ||||||||
0 a | 45 ± 8 | 0 a | 355 ± 36 | 0 a | 94 ± 12 | 0 a | 19 ± 7 | |
0.030 + M b | 705 ± 72 (7) | 0.010 + M c | 1579 ± 94 | 0.030 + M d | 976 ± 38 (8) | 0.030 + M e | 378 ± 49*** (41) | |
0.060+ M b | 612 ± 43 (19) | 0.030 + M c | 1395 ± 70 | 0.060 + M d | 915 ± 44 (14) | 0.060 + M e | 405 ± 51*** (37) | |
0.120 + M b | 623 ± 38 (17) | 0.060 + M c | 1499 ± 89 | 0.120 + M d | 739 ± 40*** (31) | 0.120 + M e | 332 ± 35*** (48) | |
0.250 + M b | 593 ± 51 (21) | 0.120 + M c | 1432 ± 79 | 0.250 + M d | 781 ± 52** (27) | 0.250 + M e | 268 ± 43*** (58) | |
0.500 + M b | 483 ± 40* (36) | 0.250 + M c | 1440 ± 65 | 0.500 + M d | 680 ± 36*** (36) | 0.500 + M e | 157 ± 29*** (76) | |
M b | 755 ± 89 | M c | 1251 ± 82 | M d | 1064 ± 101 | M e | 640 ± 49 | |
B. intermedia | ||||||||
0 a | 53 ± 12 | 0 a | 317 ± 55 | 0 a | 94 ± 12 | 0 a | 19 ± 7 | |
0.010 + M b | 677 ± 67* (24) | 0.007 + M c | 1593 ± 71 (5) | 0.010 + M d | 981 ± 61 (8) | 0.010 + M e | 338 ± 37*** (47) | |
0.030 + M b | 679 ± 61* (24) | 0.010 + M c | 1584 ± 45 (5) | 0.030 + M d | 993 ± 32 (7) | 0.030 + M e | 385 ± 48*** (40) | |
0.060 + M b | 665 ± 82* (26) | 0.030 + M c | 1504 ± 68 (10) | 0.060 + M d | 958 ± 20 (10) | 0.060 + M e | 293 ± 27*** (54) | |
0.120 + M b | 632 ± 54** (29) | 0.060 + M c | 1443 ± 82 (14) | 0.120 + M d | 864 ± 39** (19) | 0.120 + M e | 253 ± 19*** (60) | |
0.250 + M b | 621 ± 42** (30) | 0.120 + M c | 1409 ± 72 (16) | 0.250 + M d | 725 ± 23*** (32) | 0.250 + M e | 148 ± 23*** (77) | |
M b | 893 ± 79 | M c | 1672 ± 102 | M d | 1064 ± 101 | M e | 640 ± 49 |