Phenolic contents, antioxidant and anticholinesterase potentials of crude extract, subsequent fractions and crude saponins from Polygonum hydropiper L

Table 2 AChE inhibitory potential of plant extracts

Samples	Concentrations (μg/ml)	Percent inhibition (mean ± SEM)	IC₅₀(μg/ml)
Ph.Cr	1000	86.87 ± 1.27	330
	500	80.62 ± 1.67**
	250	31.31 ± 0.58***
	125	27. 22 ± 1.28***
Ph.Hex	1000	87.49 ± 0.60	35
	500	76.28 ± 1.94**
	250	70.08 ± 1.04***
	125	65.37 ± 0.56***
Ph.Chf	1000	84.76 ± 0.61	55
	500	81.36 ± 1.31**
	250	66.27 ± 1.06***
	125	61.17 ± 1.30***
Ph.EtAc	1000	79.95 ± 2.01**	310
	500	58.89 ± 4.82***
	250	46.22 ± 1.28***
	125	40.51 ± 0.54***
Ph.Bt	1000	75.52 ± 3.28**	240
	500	55.59 ± 3.28***
	250	50.83 ± 1.21***
	125	45.87 ± 0.85***
Ph.Aq	1000	67.60 ± 1.63***	100
	500	64.42 ± 1.89***
	250	58.25 ± 1.40***
	125	51.10 ± 0.60***
Ph.Sp	1000	87.58 ± 0.63	108
	500	86.61 ± 0.43
	250	60.93 ± 0.67***
	125	53.65 ± 0.91***
	1000	95.83 ± 1.21
Galanthamine	500	93.58 ± 0.63	< 0.1
	250	87.45 ± 0.90
	125	83.08 ± 1.04

Result expressed as% inhibition (mean ± SEM of n = 3) and IC₅₀ values. Values significantly different as compare to positive control, *:P < 0.05, **:P < 0.01, ***:P < 0.001.

ISSN: 2662-7671