Skip to main content

Advertisement

Table 1 Differentially expressed genes after treatment with Gelsemium s. 2c in SH-SY5Y cells

From: Extreme sensitivity of gene expression in human SH-SY5Y neurocytes to ultra-low doses of Gelsemium sempervirens

Gene ID Transcript ID Symbol Log2 fold change p 1 Description
7940 AF000424 LST1 -0.84 ± 0.14 0.04 Leukocyte specific transcript 1
390113 NM_001004726 OR4X1 -0.83 ± 0.06 0.01 Olfactory receptor, family 4, subfamily X, member 1
23746 AJ830742 AIPL1 -0.82 ± 0.16 0.04 Aryl hydrocarbon receptor interacting protein-like 1
284498 AL833920 C1orf167 -0.80 ± 0.17 0.05 Chromosome 1 open reading frame 167
221191 AK058068 Klkbl4 -0.79 ± 0.12 0.04 Plasma kallikrein-like protein 4
26658 NM_012377 OR7C2 -0.77 ± 0.07 0.01 Olfactory receptor, family 7, subfamily C, member 2
112401 BC039318 BIRC8 -0.76 ± 0.11 0.00 Baculoviral IAP repeat-containing 8
2848 NM_005298 GPR25 -0.75 ± 0.15 0.02 G protein-coupled receptor 25
55803 NM_018404 ADAP2 -0.75 ± 0.11 0.02 ArfGAP with dual PH domains 2
386676 NM_198690 KRTAP10-9 -0.73 ± 0.12 0.04 Keratin associated protein 10-9
4353 X04876 MPO -0.72 ± 0.15 0.04 Myeloperoxidase
N/A AY358413 N/A -0.71 ± 0.18 0.02 Homo sapiens clone DNA59853 trypsin inhibitor
392391 NM_001001923 OR5C1 -0.71 ± 0.05 0.04 Olfactory receptor, family 5, subfamily C, member 1
N/A AK094115 N/A -0.70 ± 0.11 0.04 Homo sapiens cDNA FLJ36796 fis, clone ADRGL2006817
55287 BC020658 TMEM40 -0.70 ± 0.15 0.02 Transmembrane protein 40
54209 NM_018965 TREM2 -0.69 ± 0.10 0.02 Triggering receptor expressed on myeloid cells 2
150365 AK097834 RP5-821D11.2 -0.68 ± 0.17 0.02 Similar to mouse meiosis defective 1 gene
400934 NM_207478 FLJ44385 -0.68 ± 0.09 0.04 FLJ44385 protein
255061 NM_170685 TAC4 -0.67 ± 0.14 0.01 Tachykinin 4 (hemokinin)
644065 XM_931993 LOC644065 -0.65 ± 0.23 0.04 Hypothetical protein LOC644065
1339 NM_005205 COX6A2 -0.64 ± 0.17 0.01 Cytochrome c oxidase subunit VIa polypeptide 2
N/A AK128093 N/A -0.63 ± 0.09 0.04 Homo sapiens cDNA FLJ46214 fis, clone TESTI4012623.
53841 AY358368 CDHR5 -0.63 ± 0.11 0.04 Mucin-like protocadherin
9332 NM_004244 CD163 -0.63 ± 0.18 0.03 CD163 molecule
441239 XM_499305 LOC441239 -0.63 ± 0.22 0.05 Hypothetical gene supported by BC063653
7164 NM_001003397 TPD52L1 -0.62 ± 0.09 0.02 Tumor protein D52-like 1
11136 NM_014270 SLC7A9 -0.62 ± 0.09 0.04 Solute carrier family 7 member 9
389084 NM_206895 UNQ830 -0.62 ± 0.11 0.04 ASCL830
400224 XM_375090 FLJ44817 -0.62 ± 0.20 0.04 Similar to pleckstrin homology domain protein (5 V327)
647240 XM_934559 LOC647240 -0.60 ± 0.06 0.00 Hypothetical protein LOC647240
846 BC104999 CASR -0.59 ± 0.06 0.00 Calcium-sensing receptor
116123 NM_138784 RP11-45 J16.2 -0.58 ± 0.09 0.04 Flavin-containing monooxygenase pseudogene
644280 XM_497769 LOC644280 -0.58 ± 0.06 0.05 Hypothetical protein LOC644280
57452 AB032956 GALNTL1 -0.57 ± 0.17 0.05 Alpha-D-galactosamine N-acetylgalactosaminyltransferase
414301 NM_001001711 DDI1 -0.56 ± 0.11 0.04 DDI1, DNA-damage inducible 1, homolog 1 (S. cerevisiae)
116535 BC016964 MRGPRF -0.55 ± 0.17 0.01 MAS-related GPR, member F
8811 NM_003857 GALR2 -0.55 ± 0.07 0.04 Galanin receptor 2
10880 NM_006686 ACTL7B -0.55 ± 0.12 0.04 Actin-like 7B
6368 NM_145898 CCL23 -0.55 ± 0.11 0.05 Chemokine (C-C motif) ligand 23
64581 BC071746 CLEC7A -0.54 ± 0.08 0.04 C-type lectin domain family 7, member A
644003 XM_927256 LOC644003 -0.54 ± 0.11 0.04 Similar to Mucin-2 precursor (Intestinal mucin 2)
643514 XM_931594 LOC643514 -0.54 ± 0.10 0.03 Hypothetical protein LOC643514
374569 XM_935431 LOC374569 -0.54 ± 0.07 0.04 Similar to Lysophospholipase
84504 BC101635 NKX6-2 -0.53 ± 0.13 0.03 NK6 transcription factor related, locus 2 (Drosophila)
732 NM_000066 C8B -0.53 ± 0.06 0.05 Complement component 8, beta polypeptide
146336 NM_182510 FLJ32252 -0.52 ± 0.03 0.01 Hypothetical protein FLJ32252
150763 BC042847 LOC150763 -0.51 ± 0.10 0.04 Hypothetical protein LOC150763
2020 NM_001427 EN2 -0.51 ± 0.08 0.04 Engrailed homolog 2
646258 XM_929203 LOC646258 -0.51 ± 0.11 0.04 Hypothetical protein LOC646258
154872 NM_001024603 LOC154872 0.51 ± 0.10 0.03 Hypothetical LOC154872
400866 NM_001001789 C21orf24 0.52 ± 0.12 0.05 Chromosome 21 open reading frame 24
9457 NM_020482 FHL5 0.55 ± 0.19 0.04 Four and a half LIM domains 5
55816 NM_018431 DOK5 0.56 ± 0.04 0.03 Docking protein 5
1446 NM_001890 CSN1S1 0.57 ± 0.09 0.04 Casein alpha s1
285600 AK130941 KIAA0825 0.63 ± 0.06 0.01 KIAA0825 protein
57538 NM_020778 ALPK3 0.76 ± 0.10 0.01 Alpha-kinase 3
  1. The table includes the genes with absolute Log2 fold change higher than 0.5. Each gene is described via GeneBank accession number (Gene ID), Gene symbol (Symbol), NimbleGen array transcript designation (Transcript ID). The log2 fold change of expression compared to mean control vehicle-treated cells is displayed as mean ± SEM (n = 4 replicate experiments). 1adjusted p value with Benjamini-Hochberg correction, obtained by Limma statistical test.