In vitro and in vivo antidermatophytic activity of the dichloromethane-methanol (1:1 v/v) extract from the stem bark of Polyscias fulva Hiern (Araliaceae)

Table 3 Diameter of the inhibition zones (mm) of CH ₂ Cl ₂ -MeOH (1:1v/v) crude extract and fractions of the stem bark of Polyscias fulva

Microorganisms	Diameter of inhibition zones ± Standard deviation (mm)
Microorganisms	Crude extract	Hexane fraction	Ethyl acetate fraction	n-butanol fraction	Residue fraction	Griseofulvin (10 μg)
T. mentagrophytes	28.0 ± 0.5^b	0,0 ± 0.0^a	29.0 ±0.5^c	29.0 ±0.5^c	28.1 ±0.2^b	34.75±0.25^d
T. ajelloi	28.0 ± 0.4^b	7.0 ± 0.3^a	28.5±0.5^b	28.5±0.5^b	28.0 ± 0.2^b	30.5±0.5^c
T. rubrum	24.0 ± 0.4^c	0.0 ± 0.0^a	24.5±0.5^c	24.4±0.2^c	23.0 ±0.4^b	30±0.5^d
T. equinum	25.4 ± 0.4^c	0.0 ± 0.0^a	25.4±0.4^c	25.0 ±0.5^c	24.5±0.5^c	27.5±0.5^d
T. terrestre	25.0 ± 0.5^c	0.0 ± 0.0^a	22.0 ±0.3^c	21.0 ±0.3^b	22.0 ±0.5^c	35.83±0.28^e
E. flocosum	21.5 ± 0.5^b	20.0 ± 0.5^a	23.0 ±0.5^c	23.0 ±0.5^c	22.0 ±0.5^b	35±0.5^d
M. gypseum	20.3 ± 0.3^b	0.0 ± 0.0^a	20.2±0.2^b	21.0 ±0.3^c	21.0 ±0.5^c	34.7±0.20^d
M. audouinii	28.1 ± 0.3^b	0.0 ± 0.0^a	29.0 ±0.5^c	29.1 ±0.2^c	28.1±0.3^b	34.75±0.25^d

The results are the mean values of triplicate tests. Across the line, values affected by the same letter superscript are not significantly different (test of Waller-Duncan (p > 0.05).

ISSN: 2662-7671