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Table 1 IC 50 values of P2Et fraction, gallic acid, and doxorubicin in 4T1 and normal cells (gingival fibroblasts and PBMC) estimated using the MTT assay

From: Gallotannin-rich Caesalpinia spinosa fraction decreases the primary tumor and factors associated with poor prognosis in a murine breast cancer model

 

IC50values after treatment with the following compounds

Cell Type

P2Et fraction*

Gallic acid*

Doxorubicin*

4T1

34.1 ± 1.6

96.2 ± 0.0

0.5 ± 0.1

PBMC + PHA

> 125 ± 1.0

ND

2023 ± 0.2

Fibroblasts

> 125 ± 1.0

ND

0.4 ± 0.1

  1. *Concentration (μg/mL) ± SEM.
  2. ND = not done.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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