Mondia whitei (Periplocaceae) prevents and Guibourtia tessmannii (Caesalpiniaceae) facilitates fictive ejaculation in spinal male rats

Table 2 Effects of urethral and penile stimulations, intravenous administration of drugs on the number, frequency and latency of contractions of the bulbospongiosus muscles in spinal rats

Treatment	Number of contractions (N)	Frequency of contractions (N s-¹)	Latency of contractions (s)
Urethral stimulation	4.57 ± 0.81	0.45 ± 0.03	28.11 ± 5.65
Penile stimulation	8.52 ± 1.59	0.34 ± 0.05	2.53 ± 0.80
Dopamine (0.1 μM/kg)	9.80 ± 0.86^###	0.41 ± 0.02	11.89 ± 2.35^###,ФФФ
Aqueous extract of Guibourtia tessmannii 20 mg/kg	4.80 ± 1.15^Ф,***	0.38 ± 0.05	284.02 ± 75.10^{###,ФФФ,***}
Methanolic extract of Guibourtia tessmannii 20 mg/kg	3.80 ± 0.93^ФФ,***	0.38 ± 0.04	150.86 ± 36.98^{###,ФФФ,***}
Aqueous extract of Mondia whitei (20 mg/kg) plus dopamine (0.1 μM/kg)	6.66 ± 0.66	0.48 ± 0.06	ND
Hexane extract of Mondia whitei (20 mg/kg) plus dopamine (0.1 μM/kg)	6.67 ± 0.89	0.46 ± 0.02	ND

Number of rats per group = 5. All values are expressed as mean ± SEM. Urethral and penile stimulations represent the mean value of all urethral and penile stimulations carried out in this study (three stimulations per rat).
^### p < 0.001 significantly different compared with urethral stimulation.
^Ф p < 0.05, ^ФФ p < 0.01 and ^ФФФ p < 0.001significantly different compared with penile stimulation.
^*p < 0.05, ^**p < 0.01 and ^*** p < 0.001 significantly different compared with dopamine.
For each rat, the frequency of contractions of the bulbospongiosus muscles was calculated by dividing the number of contractions (N) by the duration of the motor train and the latency was observed during EMG recording. ND = not determined.

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